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NutrEval First Morning Void
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NutrEval First Morning Void
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Freedom Functional Medicine - NutrEval First Morning Void

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The NutrEval® is both a blood and urine profile that evaluates over 125 biomarkers and assesses the body's functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support, and other select nutrients. Personalized recommendations for nutrients are determined by using an algorithm based on your patient's test findings. Functional pillars with a built-in scoring system guide the need for therapeutic support in areas of methylation, toxic exposure, mitochondrial dysfunction, fatty acid imbalances, and oxidative stress. The NutrEval Plasma and NutrEval FMV (first morning void) differ based on which sample type is used to measure amino acids, plasma or urine.

We also offer the Metabolomix+, a similar profile that can be collected entirely at home – no blood draw required.

Which patients might benefit from functional nutritional testing?

According to the World Health Organization, every country in the world is affected by one or more forms of malnutrition.[1] Nutritional imbalances are often root cause contributors to disease. Correcting these imbalances can result in optimized health and well-being of your patients.

Common clinical indications for testing include:

  • Mood disorders [2,3,4,5,6,7]
  • Cardiovascular disease [8,9]
  • Obesity/ Insulin resistance/ Type 2 Diabetes [10,11,12,13]
  • Fatigue [14,15,16,17]
  • Weight Issues/ Dietary Guidance [13,18]
  • Malnutrition (often observed in the elderly) [19,20]
  • Maldigestion/Malabsorption
  • Athletic performance [21,22]
  • Physical trauma/healing [16,23,24]

*Testing is not performed in patients under 2 years old.

About the NutrEval Profile

The NutrEval report categorizes results into several metabolic areas (see sample reports in the Support Materials for individual analytes):

  • Personalized Results Overview and Nutrient Need Overview
    • Functional Imbalance Scores in areas of methylation, toxic exposure, mitochondrial dysfunction, fatty acid imbalances, and oxidative stress
    • Nutrient Need Overview with recommendations for antioxidants, B-vitamins, minerals, essential fatty acids, GI support, and amino acids
    • Interpretation-At-A-Glance pages provide nutritional educational support for you and your patient highlighting the function of each nutrient, cause of deficiency, complications of deficiency and food sources of the nutrient
  • Organic Acids (urine)
    • Malabsorption and Bacterial/ Yeast Dysbiosis Markers are metabolites produced by the gastrointestinal microbiome
    • Cellular Energy & Mitochondrial Metabolites are biomarkers of carbohydrate and fatty acid metabolism, and the citric acid (Kreb’s) cycle
    • Neurotransmitter Metabolites are downstream byproducts of epinephrine, norepinephrine, serotonin and dopamine
    • Vitamin Markers are specific analytes used to assess functional levels of vitamin cofactors
    • Toxin & Detoxification Markers relate to certain toxic metabolites and the body’s detoxification capacity
    • Oxalate Markers relate to kidney stone formation, oxidative stress and metabolic dysfunction
  • Oxidative Stress Markers include antioxidants glutathione (whole blood) and Coenzyme Q10 (serum), as well as the oxidative damage markers lipid peroxides and 8-OHdG (urine)
  • Amino Acids (plasma or urine)
    • Essential Amino Acids must be derived from dietary sources
    • Nonessential Amino Acids are synthesized by the body
    • Intermediary Metabolites are byproducts of amino acid metabolism
      • B Vitamin Markers are involved in biochemical reactions that specifically require B vitamins
      • Urea Cycle Markers are byproducts associated with nitrogen (ammonia) detoxification
      • Glycine/Serine Metabolites are involved in the serine-to-choline pathway and the methylation pathways
    • Dietary Peptide Related Markers can indicate incomplete protein breakdown and meat intake
  • Essential and Metabolic Fatty Acids Markers (RBCs)
    • Omega 3 Fatty Acids are essential for brain function and cardiovascular health and are anti-inflammatory
    • Omega 6 Fatty Acids are involved in the balance of inflammation
    • Omega 9 Fatty Acids are important for brain growth, nerve cell myelin, and reducing inflammation
    • Saturated Fatty Acids are involved in liproprotein metabolism and adipose tissue inflammation
    • Monounsaturated Fats include omega 7 fats and unhealthy trans fats
    • Delta-6 Desaturase Activity assesses efficiency of this enzyme to metabolize omega 6’s and omega 3’s
    • Cardiovascular Risk includes specific ratios and the Omega 3 Index
  • Elemental Markers
    • Nutrient Elements are direct measurements of copper and zinc (plasma), magnesium and potassium (RBC), and manganese and selenium (whole blood)
    • Toxic Elements (whole blood) indicate exposure to lead, mercury, arsenic or cadmium within approximately a 90-120 day timeframe
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Returns & Exchanges
Please ensure you are choosing the correct size at checkout, we are unable to accept returns for incorrect sizing. Any claims for defective items or items lost in the mail must be submitted within 15 days. Any errors on our part will be covered at our expense.
Contact us if you have any questions.